6-fluoro-1H-indazol-3-carboxylic acid

6-fluoro-1H-indazol-3-carboxylic acid - Names and Identifiers

Name	6-FLUORO-1H-INDAZOLE-3-CARBOXYLIC ACID
Synonyms	6-FLUORO-3-INDAZOLECARBOXYLIC ACID 6-FLUORO-3-INDOZOLE-CARBOXYLIC ACID 6-fluoro-1H-indazol-3-carboxylic acid 6-FLUORO-1H-INDAZOLE-3-CARBOXYLIC ACID 6-FLUORO-3-(1H)INDAZOLE CARBOXYLIC ACID 1H-Indazole-3-carboxylic acid, 6-fluoro-
CAS	129295-30-3
InChI	InChI=1/C8H5FN2O2/c9-4-1-2-5-6(3-4)10-11-7(5)8(12)13/h1-3H,(H,10,11)(H,12,13)

6-fluoro-1H-indazol-3-carboxylic acid - Physico-chemical Properties

Molecular Formula	C8H5FN2O2
Molar Mass	180.14
Density	1.610±0.06 g/cm3(Predicted)
Boling Point	445.9±25.0 °C(Predicted)
Flash Point	223.443°C
Vapor Presure	0mmHg at 25°C
pKa	2.86±0.10(Predicted)
Storage Condition	Room Temprature
Refractive Index	1.707

6-fluoro-1H-indazol-3-carboxylic acid - Introduction

6-Fluoro-1H-indazole-3-carboxylic acid is an organic compound with the chemical formula C3H2FNO2. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: 6-fluoro-1H-indazole-3-carboxylic acid as a white to light yellow crystalline solid.
-Solubility: It has low solubility in water and is soluble in organic solvents such as alcohols and ethers.
-Stability: It is relatively stable, but may decompose at high temperatures.

Use:
-6-Fluoro-1H-indazole-3-carboxylic acid can be used as a chemical reagent for the synthesis of other compounds in organic synthesis.
-It also has certain applications in the field of medicine, for example, it can be used to synthesize antibacterial drugs.

Preparation Method:
The preparation method of 6-fluoro-1H-indazole-3-carboxylic acid usually includes the following steps:
1. An appropriate amount of 3-carboxyindazole is reacted with hydrofluoric acid, and hydrofluoric acid gas is introduced under appropriate conditions.
2. During the reaction, the reaction mixture is gradually heated to allow the reaction to proceed.
3. Finally, the obtained product was purified by crystallization to obtain 6-fluoro-1H-indazole-3-carboxylic acid.

Safety Information:
The safety of 6-fluoro-1H-indazole-3-carboxylic acid has not been fully evaluated. When in use, should follow the general chemical safety procedures.
-It may be irritating to the skin, eyes and respiratory system, so use appropriate protective equipment such as gloves, goggles and respirators.
-Incorrect use or contact may cause physical discomfort. Care should be taken to avoid swallowing, inhaling or touching the skin. If accidental contact occurs, immediately flush the affected area with plenty of water and seek medical help.

Last Update：2024-04-09 21:00:56